Title : Mutations that affect vacuole biogenesis inhibit proliferation of the endoplasmic reticulum in Saccharomyces cerevisiae.

Pub. Date : 2002 Apr

PMID : 11973291






1 Functional Relationships(s)
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1 In yeast, increased levels of the sterol biosynthetic enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase isozyme, Hmg1p, induce assembly of nuclear-associated ER membranes called karmellae. Sterols hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 Saccharomyces cerevisiae S288C