Pub. Date : 2002 Apr 30
PMID : 11969406
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Uniformly (13)C-labeled long-chain fatty acids were used to probe ligand binding to rat liver fatty acid-binding protein (LFABP), an atypical member of the fatty acid-binding protein (FABP) family that binds more than one molecule of long-chain fatty acid, accommodates a variety of diverse ligands, and exhibits diffusion-mediated lipid transport to membranes. | Fatty Acids | fatty acid binding protein 1 | Rattus norvegicus |
2 | Two sets of (1)H-(13)C resonances were found in a titration series of NMR spectra for oleate-LFABP complexes, indicating that two molecules of the fatty acid are situated in the protein cavity. | Fatty Acids | fatty acid binding protein 1 | Rattus norvegicus |
3 | In light of these NMR measurements, possible molecular mechanisms for the ligand-exchange process are evaluated and implications for the anomalous fatty acid transport mechanism of LFABP are discussed. | Fatty Acids | fatty acid binding protein 1 | Rattus norvegicus |