Title : Non-genomic stimulation of tyrosine phosphorylation cascades by 1,25(OH)(2)D(3) by VDR-dependent and -independent mechanisms in muscle cells.

Pub. Date : 2002 May

PMID : 11960624






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Recent investigations of our laboratory have demonstrated that 1,25(OH)(2)D(3) rapidly stimulates in muscle cells tyrosine phosphorylation of PLC-gamma and the growth-related proteins MAPK and c-myc. Tyrosine MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 We have now obtained evidence using antisense technology indicating that VDR-dependent activation of Src mediates the fast stimulation of tyrosine phosphorylation of c-myc elicited by the hormone. Tyrosine MYC proto-oncogene, bHLH transcription factor Homo sapiens