Title : Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.

Pub. Date : 2002 May

PMID : 11950782






1 Functional Relationships(s)
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1 Enzyme activity was reduced 78.1 +/- 0.2% by 50 microM thioTEPA when CYP2B6 activity was measured by following the metabolism of 200 microM S-mephenytoin to nirvanol. ethylphenylhydantoin cytochrome P450 family 2 subfamily B member 6 Homo sapiens