Title : Modification of RNA by mRNA guanylyltransferase and mRNA (guanine-7-)methyltransferase from vaccinia virions.

Pub. Date : 1975 Dec 25

PMID : 1194287






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The properties of this reaction are: (a) of the four nucleoside triphosphates only GTP is a donor, (b) mRNA with two phosphates at the 5" terminus is an acceptor while RNA with a single 5"-terminal phosphate is not, (c) Mg2+ is required, (d) the pH optimum is 7.8, (e) PP1 is a strong inhibitor, and (f) the reverse reaction, namely the formation of GTP from PP1 and RNA containing the 5"-terminal structure G(5")pppN-, readily occurs. nucleoside triphosphates inorganic pyrophosphatase 1 Homo sapiens
2 The properties of this reaction are: (a) of the four nucleoside triphosphates only GTP is a donor, (b) mRNA with two phosphates at the 5" terminus is an acceptor while RNA with a single 5"-terminal phosphate is not, (c) Mg2+ is required, (d) the pH optimum is 7.8, (e) PP1 is a strong inhibitor, and (f) the reverse reaction, namely the formation of GTP from PP1 and RNA containing the 5"-terminal structure G(5")pppN-, readily occurs. nucleoside triphosphates inorganic pyrophosphatase 1 Homo sapiens