Title : N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk.

Pub. Date : 2002 Apr

PMID : 11927838






3 Functional Relationships(s)
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1 We observed previously that polymorphisms in glutathione S-transferase (GST) genes modified allergic responses to diisocyanate exposure. 4,4'-diphenylmethane diisocyanate glutathione S-transferase kappa 1 Homo sapiens
2 We observed previously that polymorphisms in glutathione S-transferase (GST) genes modified allergic responses to diisocyanate exposure. 4,4'-diphenylmethane diisocyanate glutathione S-transferase kappa 1 Homo sapiens
3 The results suggest for the first time that in addition to GSTs, the NATs play an important role in inception of asthmatic reactions related to occupational exposure to diisocyanates. 4,4'-diphenylmethane diisocyanate glutathione S-transferase kappa 1 Homo sapiens