Pub. Date : 2002 Aug 9
PMID : 11925449
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Introducing an Ala(19) mutation into the p53(F270A) protein abolished both RNA.MDM2 complex binding and hyper-ubiquitination in vivo, thus indicating that p53(F270A) protein hyper-ubiquitination depends upon MDM2 binding to its primary site in the BOX-I domain. | Alanine | tumor protein p53 | Homo sapiens |
2 | Introducing an Ala(19) mutation into the p53(F270A) protein abolished both RNA.MDM2 complex binding and hyper-ubiquitination in vivo, thus indicating that p53(F270A) protein hyper-ubiquitination depends upon MDM2 binding to its primary site in the BOX-I domain. | Alanine | tumor protein p53 | Homo sapiens |