Title : Neoplastic transformation of human breast epithelial cells by estrogens and chemical carcinogens.

Pub. Date : 2002

PMID : 11921196






1 Functional Relationships(s)
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1 Interestingly, endogenous 17beta-estradiol (E(2)) is metabolized by the cytochrome P450 enzyme isoforms CYP1A1 and CYP1B1, which also activate benzo[a]pyrene (B[a]P), a carcinogen contained in cigarette smoke. Benzo(a)pyrene cytochrome P450 family 1 subfamily B member 1 Homo sapiens