Title : Proteolysis involving matrix metalloproteinase 13 (collagenase-3) is required for chondrocyte differentiation that is associated with matrix mineralization.

Pub. Date : 2002 Apr

PMID : 11918221






1 Functional Relationships(s)
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Protein Name
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1 A nontoxic carboxylate inhibitor of MMP-13 prevents this differentiation; it suppresses expression of type X collagen, Cbfal, and MMP-13 and inhibits increased calcium incorporation in addition to inhibiting degradation of type II collagen in the extracellular matrix. carboxylate matrix metallopeptidase 13 Bos taurus