Title : Binding of homogeneous cytochrome b5 to rat liver microsomes. Effect on N-demethylation reactions.

Pub. Date : 1975 Nov 20

PMID : 1191670






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Incubation of rat homogeneous detergent-solubilized cytochrome b5 with rat liver microsomes resulted in specific binding of the hemoprotein which was rapidly reduced by NADH. NAD cytochrome b5 type A Rattus norvegicus
2 However, the extra-bound detergent-solubilized cytochrome b5 did inhibit NADPH-dependent N-demethylations, the NADH synergism and NADPH cytochrome P-450 reductase activity. NAD cytochrome b5 type A Rattus norvegicus