Pub. Date : 2002 Apr 1
PMID : 11903042
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt. | Glycosaminoglycans | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Furthermore, expression of dominant-negative Akt abrogated endogenous Akt activity, Rab3D phosphorylation and GAG synthesis, whereas expression of constitutively activated Akt stimulated Rab3D phosphorylation and GAG synthesis in the absence of PDGF-BB. | Glycosaminoglycans | AKT serine/threonine kinase 1 | Homo sapiens |
3 | Furthermore, expression of dominant-negative Akt abrogated endogenous Akt activity, Rab3D phosphorylation and GAG synthesis, whereas expression of constitutively activated Akt stimulated Rab3D phosphorylation and GAG synthesis in the absence of PDGF-BB. | Glycosaminoglycans | AKT serine/threonine kinase 1 | Homo sapiens |