Title : Bax-induction alone is sufficient to activate apoptosis cascade in wild-type Bax-bearing K562 cells, and the initiation of apoptosis requires simultaneous caspase activation.

Pub. Date : 2002 Apr

PMID : 11894116






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A pancaspase inhibitor, zVAD-fmk, which has no effect on mitochondrial cytochrome c release and mitochondrial membrane potential change inhibited the apoptotic events in the presence of overexpressed Bax in mitochondria. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone BCL2 associated X, apoptosis regulator Homo sapiens