Title : Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

Pub. Date : 2002 Mar

PMID : 11875499






1 Functional Relationships(s)
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1 Chemotherapeutic agents upregulated expression of the Apo2L/TRAIL receptor DR5 and the Bax homolog Bak in Baxminus sign/minus sign cells, and restored Apo2L/TRAIL sensitivity in vitro and in vivo. bakuchiol BCL2 associated X, apoptosis regulator Homo sapiens