Title : Nicotine reduces the incidence of type I diabetes in mice.

Pub. Date : 2002 Mar

PMID : 11861793






2 Functional Relationships(s)
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1 The pancreatic levels of the Th1 cytokines interleukin (IL)-12, IL-1, tumor necrosis factor (TNF)-alpha, and interferon (IFN)-gamma were increased in both MLDS-induced and spontaneous NOD diabetes, an effect prevented by nicotine treatment. Nicotine negative elongation factor complex member C/D, Th1l Mus musculus
2 Nicotine treatment reduces the incidence of type I diabetes in two animal models by changing the profile of pancreatic cytokine expression from Th1 to Th2. Nicotine negative elongation factor complex member C/D, Th1l Mus musculus