Title : Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.

Pub. Date : 2002 Feb

PMID : 11861317






4 Functional Relationships(s)
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1 Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
3 Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
4 Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis