Pub. Date : 2002 Feb 13
PMID : 11852106
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction. | Curcumin | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | Further experiments using p53-null MDAH041 cell as well as low and high p53-expressing TR9-7 cell, in which p53 expression is under tight control of tetracycline, established that curcumin induced apoptosis in tumor cells via a p53-dependent pathway in which Bax is the downstream effector of p53. | Curcumin | BCL2 associated X, apoptosis regulator | Homo sapiens |