Title : Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus.

Pub. Date : 2002 Feb

PMID : 11831546






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1 The authors assessed the mutual influence of the immunosuppressant everolimus (Certican) and the HMG-CoA reductase inhibitors atorvastatin and pravastatin when coadministered based on pharmacokinetic and pharmacodynamic measures. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens