Title : Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines.

Pub. Date : 2002 Feb 1

PMID : 11830551






1 Functional Relationships(s)
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1 Blockade of NF-kappaB activation by MG132, sulfasalazine, or an IkappaBalpha superrepressor disrupted the IL-1beta-mediated amplification loop and the accompanying chemoresistance. benzyloxycarbonylleucyl-leucyl-leucine aldehyde interleukin 1 beta Homo sapiens