Title : Decrease of epidermal histidase activity by tumor-promoting phorbol esters.

Pub. Date : 1975 Nov

PMID : 1182705






2 Functional Relationships(s)
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1 The relationship of this histidase depression to tumor promotion and not initiation is further indicated by the finding that (a) Tween 60, a structurally unrelated tumor promotor, also produced a decrease in histidase; and (b) the tumor initiator urethan and an initiating dose of 9,10-dimethybenz(a)anthracene showed no effects on histadase activity. Polysorbates histidine ammonia lyase Mus musculus
2 The relationship of this histidase depression to tumor promotion and not initiation is further indicated by the finding that (a) Tween 60, a structurally unrelated tumor promotor, also produced a decrease in histidase; and (b) the tumor initiator urethan and an initiating dose of 9,10-dimethybenz(a)anthracene showed no effects on histadase activity. Polysorbates histidine ammonia lyase Mus musculus