Title : Human monocyte-derived dendritic cells are deficient in prostaglandin E2 production.

Pub. Date : 2002 Jan 30

PMID : 11821061






3 Functional Relationships(s)
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1 We show here that one effect of interleukin (IL)-4, which is used together with GM-CSF to generate moDCs, is the suppression of endogenous PGE2 production in moDCs. Dinoprostone interleukin 4 Homo sapiens
2 IL-4-mediated suppression of PGE2 biosynthesis in human moDCs explains the previously reported maturation-enhancing effect of exogenous PGE2. Dinoprostone interleukin 4 Homo sapiens
3 IL-4-mediated suppression of PGE2 biosynthesis in human moDCs explains the previously reported maturation-enhancing effect of exogenous PGE2. Dinoprostone interleukin 4 Homo sapiens