Title : p53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress.

Pub. Date : 2002 Feb

PMID : 11809417






2 Functional Relationships(s)
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1 Pretreatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of the redox sensitive transcription factor NF-kappa B, abrogated the increased expression of p53 protein in response to H(2)O(2), and enhanced cell survival. pyrrolidine dithiocarbamic acid tumor protein p53 Homo sapiens
2 Pretreatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of the redox sensitive transcription factor NF-kappa B, abrogated the increased expression of p53 protein in response to H(2)O(2), and enhanced cell survival. pyrrolidine dithiocarbamic acid tumor protein p53 Homo sapiens