Title : [Mechanism of the activation of extracellular signal-regulated kinase (ERK) in prostate cancer cell lines with different metastatic potential].

Pub. Date : 2001 Feb 25

PMID : 11798872






1 Functional Relationships(s)
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1 The activation of ERK1/2 by ATP was blocked by the P2 purinoceptor antagonist, suramin with an inhibitory rate of 82% +/- 9% for 1E8 and an inhibitory rate of 81% +/- 6% for 2B4. Suramin pyrimidinergic receptor P2Y6 Homo sapiens