Title : Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction.

Pub. Date : 2001 Dec 31

PMID : 11795493






1 Functional Relationships(s)
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1 In the U-937 cells treated with DZA, cytochrome c release from mitochondria and subsequent activation of caspase-9, -8 and -3 were observed before the induction of apoptosis. 3-deazaadenosine cytochrome c, somatic Homo sapiens