Pub. Date : 2001 Dec 31
PMID : 11795493
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction. | 3-deazaadenosine | caspase 3 | Homo sapiens |
| 2 | 3-Deazaadenosine (DZA), a cellular methylation blocker was reported to induce the caspase-3-like activities-dependent apoptosis in U-937 cells. | 3-deazaadenosine | caspase 3 | Homo sapiens |
| 3 | 3-Deazaadenosine (DZA), a cellular methylation blocker was reported to induce the caspase-3-like activities-dependent apoptosis in U-937 cells. | 3-deazaadenosine | caspase 3 | Homo sapiens |
| 4 | Taken together, these results suggest that in the DZA-induced apoptosis, caspase-8 may serve as an executioner caspase and be activated downstream of both caspase-3 and caspase-9, independently of Fas receptor-ligand interaction. | 3-deazaadenosine | caspase 3 | Homo sapiens |