Title : Small variations in the length of the cytoplasmic domain of the simian immunodeficiency virus transmembrane protein drastically affect envelope incorporation and virus entry.

Pub. Date : 2001 Nov 20

PMID : 11779349






2 Functional Relationships(s)
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1 When the ability of the Env mutants to associate with SIV Gag particles was examined, we found that deletion of 20 to 80 residues from the carboxyl terminus of the SIV TM cytoplasmic tail abrogated the incorporation of the Env glycoprotein into particles. Glycosaminoglycans endogenous retrovirus group K member 20 Homo sapiens
2 By contrast, further truncation of the SIV TM protein by 100 to 140 amino acids restored the ability of the Env protein to associate with Gag particles. Glycosaminoglycans endogenous retrovirus group K member 20 Homo sapiens