Title : The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study.

Pub. Date : 2002 Jan-Mar

PMID : 11772521






1 Functional Relationships(s)
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1 More specifically, under the influence of trichostatin A, PBL showed increasing H1(0) synthesis rates and increasing levels of histone H4 acetylation as a function of increasing age of the donor. Pentane-2,2,4,4-Tetrol H1.0 linker histone Homo sapiens