Title : Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism.

Pub. Date : 2001 Dec

PMID : 11740343






1 Functional Relationships(s)
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1 Testosterone was a poor substrate and activity with progesterone was 6-fold higher, but estradiol was the preferred substrate, exhibiting a greater metabolite profile with CYP1B1 than with CYP1A2. Testosterone cytochrome P450 family 1 subfamily B member 1 Homo sapiens