Pub. Date : 2001 Dec 18
PMID : 11735395
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. | Calcium | LDL receptor related protein 1 | Homo sapiens |
| 2 | Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. | Calcium | LDL receptor related protein 1 | Homo sapiens |
| 3 | We have determined the X-ray crystal structure to 1.8 A resolution of the Ca(2+) complex of complement-like repeat 7 (CR7) from the low-density lipoprotein receptor-related protein (LRP) and characterized its calcium binding properties at pH 7.4 and 5. | Calcium | LDL receptor related protein 1 | Homo sapiens |
| 4 | This suggests that a pH-dependent change in calcium affinity alone cannot be responsible for the release of bound protein ligands from the LRP at the pH prevailing in the endosome, which in turn requires one or more other pH-dependent effects for regulating protein ligand release. | Calcium | LDL receptor related protein 1 | Homo sapiens |