Title : S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers.

Pub. Date : 2002 Feb 22

PMID : 11734561






1 Functional Relationships(s)
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1 In addition, ADOMETDC overproduction in wild type parasites alleviated the toxic effects of 5"-(((Z)-4-amino-2-butenyl)methylamino)-5"-deoxyadenosine (MDL 73811), but not pentamidine, berenil, or methylglyoxyl bis(guanylhydrazone), all inhibitors of ADOMETDC activities in vitro. diminazene aceturate S-adenosylmethionine decarboxylase Leishmania donovani