Title : A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33.

Pub. Date : 2001 Dec

PMID : 11733002






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The cytoplasmic tail of siglec-10 contains four tyrosines, two of which are embedded in ITIM-signaling motifs (Y597 and Y667) and are likely involved in intracellular signaling. Tyrosine sialic acid binding Ig like lectin 10 Homo sapiens
2 The ability of tyrosine kinases to phosphorylate the cytoplasmic tyrosines was evaluated by kinase assay using wild-type siglec-10 cytoplasmic domain and Y-->F mutants. Tyrosine sialic acid binding Ig like lectin 10 Homo sapiens