Title : Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.

Pub. Date : 2002 Mar 22

PMID : 11724803






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase. Tyrosine matrix metallopeptidase 14 Homo sapiens
2 Enhanced tyrosine phosphorylation of focal adhesion kinase in cells co-expressing MT1-MMP and alpha(v)beta(3) integrin contributed to efficient adhesion and, especially, migration of cells on vitronectin, a ligand of alpha(v)beta(3) integrin. Tyrosine matrix metallopeptidase 14 Homo sapiens