Pub. Date : 2001 Dec
PMID : 11714877
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | More strikingly, CYP2B1/2 mRNA levels were increased 22-fold upon midazolam treatment, leading to an 11- to 95-fold enhancement of CYP2B enzyme activity. | Midazolam | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
2 | The induction of CYP2B1/2 mRNA levels by midazolam was dose-dependent (4.5-fold increase at 10 mg/kg). | Midazolam | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |