Title : Midazolam is a phenobarbital-like cytochrome p450 inducer in rats.

Pub. Date : 2001 Dec

PMID : 11714877






2 Functional Relationships(s)
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1 More strikingly, CYP2B1/2 mRNA levels were increased 22-fold upon midazolam treatment, leading to an 11- to 95-fold enhancement of CYP2B enzyme activity. Midazolam cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus
2 The induction of CYP2B1/2 mRNA levels by midazolam was dose-dependent (4.5-fold increase at 10 mg/kg). Midazolam cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus