Title : beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein.

Pub. Date : 2001 Oct 25

PMID : 11704825






1 Functional Relationships(s)
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1 Additionally, Z-VAD-fmk, a general inhibitor of caspases which inhibited cytochrome c release in HL-60 and HL-60/VCR cells, had no effect on AIF release in any of these cell lines, but inhibited beta(2)m-induced apoptosis in all three cell lines. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone cytochrome c, somatic Homo sapiens