Pub. Date : 2001 Dec
PMID : 11701449
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of growth hormone on renal tubular handling of sodium in healthy humans. | Sodium | growth hormone 1 | Homo sapiens |
| 2 | To investigate the mechanisms behind the water- and sodium-retaining effects of growth hormone (GH), we studied the effect of GH on 1) water and sodium homeostasis, 2) the renin-angiotensin-aldosterone system (RAAS), and 3) lithium clearance (C(Li)) with and without concomitant prostaglandin (PG) synthesis inhibition with ibuprofen. | Sodium | growth hormone 1 | Homo sapiens |
| 3 | To investigate the mechanisms behind the water- and sodium-retaining effects of growth hormone (GH), we studied the effect of GH on 1) water and sodium homeostasis, 2) the renin-angiotensin-aldosterone system (RAAS), and 3) lithium clearance (C(Li)) with and without concomitant prostaglandin (PG) synthesis inhibition with ibuprofen. | Sodium | growth hormone 1 | Homo sapiens |
| 4 | Treatment with GH increased C(Li) and changed the tubular handling of sodium and water. | Sodium | growth hormone 1 | Homo sapiens |
| 5 | The data demonstrate that GH-induced activation of the RAAS can be blocked by concomitant PG synthesis inhibition and that the tubular effects of GH include increased distal nephron sodium and water reabsorption. | Sodium | growth hormone 1 | Homo sapiens |
| 6 | The data demonstrate that GH-induced activation of the RAAS can be blocked by concomitant PG synthesis inhibition and that the tubular effects of GH include increased distal nephron sodium and water reabsorption. | Sodium | growth hormone 1 | Homo sapiens |