Title : Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men.

Pub. Date : 2001 Nov 7

PMID : 11698569






1 Functional Relationships(s)
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1 RESULTS: The risk of HCC increased with increasing concentrations of testosterone (odds ratio [OR](highest versus lowest tertile) = 2.97; 95% confidence interval [CI] = 1.54 to 5.70; P(trend) <.001) and with increasing number of the V allele of the SRD5A2 V89L polymorphism (OR(VV versus LL genotype) = 2.47; 95% CI = 1.21 to 5.03; P(trend) =.011). Testosterone steroid 5 alpha-reductase 2 Homo sapiens