Title : [Hemoglobin-induced lipid peroxidation in anemia].

Pub. Date : 2001 Jul-Aug

PMID : 11692726






2 Functional Relationships(s)
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1 Changes were studied in processes of peroxide oxidation of lipid (LPO), such as neutral lipids and phospholipids, as related to the levels of hemoglobin (Hb) and its derivatives, methemoglobin (Met-Hb) and carboxyhemoglobin (CO-Hb) in erythrocytes and blood plasma of 33 patients with iron-deficiency anemia (IDA). Peroxides hemoglobin subunit gamma 2 Homo sapiens
2 Increase in the level of Met-Hb is accompanied by an accumulation in erythrocytes of Schiff bases as the final products of phospholipids peroxidation (r = 0.586, P = 0.004), CO-Hb-substrates of LPO (r = 0.425, P = 0.049), primary (r = 0.453, P = 0.04) and secondary (r = 0.438, P = 0.048) molecular products of peroxide oxidation of neutral lipids. Peroxides hemoglobin subunit gamma 2 Homo sapiens