Title : Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells.

Pub. Date : 2001 Oct 31

PMID : 11690641






3 Functional Relationships(s)
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1 Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. Phytanic Acid cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 However, in combination with retinoic acid receptor (RAR)-ligands (all-trans-RA or synthetic Am580) phytanic acid enhanced the induction of CYP26 and RA-metabolism in comparison to treatments with all-trans-RA or Am580 alone. Phytanic Acid cytochrome P450 family 26 subfamily A member 1 Homo sapiens
3 This study indicates that food compounds such as phytanic acid and DHA that are RXR-agonists and have an impact on intestinal CYP26 gene expression and metabolism of all-trans-RA in intestinal cells. Phytanic Acid cytochrome P450 family 26 subfamily A member 1 Homo sapiens