Title : CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

Pub. Date : 2002 Jan 4

PMID : 11689561






2 Functional Relationships(s)
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1 Consistent with this, cholesterol depletion with methyl-beta-cyclodextrin substantially reduces CD38-mediated Akt activation while enhancing CD38-mediated Erk activation. Cholesterol CD38 molecule Homo sapiens
2 Consistent with this, cholesterol depletion with methyl-beta-cyclodextrin substantially reduces CD38-mediated Akt activation while enhancing CD38-mediated Erk activation. Cholesterol CD38 molecule Homo sapiens