Title : Effects of sulfation on antithrombin-thrombin/factor Xa interactions in semisynthetic low molecular weight heparins.

Pub. Date : 2001 Oct

PMID : 11668417






1 Functional Relationships(s)
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1 To gain insight into structure-activity relationships, we investigated quantitatively the interactions of a series of sulfated LMW heparins of similar molecular weights (derived from statistical desulfation of a supersulfated heparin) with the target enzymes human antithrombin (AT) and thrombin (T). Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens