Title : Thermal Cyclodimerization of Aliphatic Secondary C,N-Dilithioallylamine Derivatives.

Pub. Date : 1996 May 31

PMID : 11667225






1 Functional Relationships(s)
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1 beta-Nitrogen-functionalized vinylic organolithium compounds derived from secondary aliphatic allylamines have been found to undergo upon heating (reflux of THF) either a dimerization or a regio- and stereoselective cyclodimerization reaction affording diamino 1,4-dienes or cis-2,3-disubstituted 4-methylenepyrrolidines, respectively, according to reaction time. Allylamine suppressor of cytokine signaling 2 Homo sapiens