Title : Histamine H1 receptor-mediated inhibition of potassium-evoked release of 5-hydroxytryptamine from mouse forebrains.

Pub. Date : 2001 Oct 15

PMID : 11640963






2 Functional Relationships(s)
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1 Bicuculline, a GABA(A) antagonist, could reverse the histamine-induced inhibition of 5-HT release in wild-type mice, suggesting that H1 receptors facilitate the release of GABA, which in turn inhibits 5-HT release through GABA(A) receptors. Bicuculline gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 Mus musculus
2 Bicuculline, a GABA(A) antagonist, could reverse the histamine-induced inhibition of 5-HT release in wild-type mice, suggesting that H1 receptors facilitate the release of GABA, which in turn inhibits 5-HT release through GABA(A) receptors. Bicuculline gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 Mus musculus