Title : Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization.

Pub. Date : 2001 Nov

PMID : 11604491






1 Functional Relationships(s)
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1 We now observe that this novel alkalinization pathway is mediated by the pH regulator NHE1, as shown by the requirement for sodium, blocking by pharmacological inhibitors or use of an NHE1-deficient cell line, and the altered phosphorylation of NHE1. Sodium solute carrier family 9 member A1 Homo sapiens