Pub. Date : 2001 Oct 1
PMID : 11599000
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effect of cyclic AMP on the expression of myelin basic protein species and myelin proteolipid protein in committed oligodendrocytes: differential involvement of the transcription factor CREB. | Cyclic AMP | myelin basic protein | Homo sapiens |
2 | In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP). | Cyclic AMP | myelin basic protein | Homo sapiens |
3 | In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP). | Cyclic AMP | myelin basic protein | Homo sapiens |
4 | In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP). | Cyclic AMP | myelin basic protein | Homo sapiens |
5 | In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP). | Cyclic AMP | myelin basic protein | Homo sapiens |
6 | In this study, we have investigated whether cAMP and CREB play a role in regulating the expression of all or on the other hand particular MBP isoforms. | Cyclic AMP | myelin basic protein | Homo sapiens |
7 | The results indicated that treatment of committed oligodendrocytes with the cAMP analogue db-cAMP results in a pattern of expression of MBP-related polypeptides that most closely resembles the pattern of MBPs observed in cerebra from adult animals. | Cyclic AMP | myelin basic protein | Homo sapiens |
8 | Experiments in which CREB expression was inhibited using a CREB antisense oligonucleotide, suggested that CREB is involved in the cAMP-dependent stimulation of all the MBP isoforms. | Cyclic AMP | myelin basic protein | Homo sapiens |