Title : Cellular pharmacology of cerulenin analogs that inhibit protein palmitoylation.

Pub. Date : 2001 Oct 15

PMID : 11597568






2 Functional Relationships(s)
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1 We have described previously the synthesis of cerulenin analogs including cis-2,3-epoxy-4-oxononadecanamide (16C) and cis-2,3-epoxy-4-oxododecanamide (9C) that inhibit protein palmitoylation (Lawrence et al., J Med Chem 1999;42:4932-41), most likely through covalent alkylation of protein palmitoyltransferase. Cerulenin suppressor of cytokine signaling 2 Homo sapiens
2 We have described previously the synthesis of cerulenin analogs including cis-2,3-epoxy-4-oxononadecanamide (16C) and cis-2,3-epoxy-4-oxododecanamide (9C) that inhibit protein palmitoylation (Lawrence et al., J Med Chem 1999;42:4932-41), most likely through covalent alkylation of protein palmitoyltransferase. Cerulenin suppressor of cytokine signaling 2 Homo sapiens