Title : The androgen receptor gene and its influence on the development and progression of prostate cancer.

Pub. Date : 2001 Sep

PMID : 11592091






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The development and progression of prostate cancer are dependent on testosterone and dihydrotestosterone; the androgen receptor is the vehicle through which these androgens exert their regulation on prostate cellular proliferation and differentiation. Testosterone androgen receptor Homo sapiens
2 In addition, androgen receptor somatic mutations can result in receptors that have altered binding specificity when compared with wild-type receptors and heightened affinity for hormones other than testosterone and dihydrotestosterone. Testosterone androgen receptor Homo sapiens