Title : A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle.

Pub. Date : 2001 Oct 2

PMID : 11591318






1 Functional Relationships(s)
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1 This Pin2/TRF1 activity can be significantly potentiated by the microtubule-disrupting agent nocodazole [12] but is suppressed by phosphorylation of Pin2/TRF1 by ATM; this negative regulation is important for preventing apoptosis upon DNA damage [13]. Nocodazole ATM serine/threonine kinase Homo sapiens