Title : The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols.

Pub. Date : 2001 Nov 30

PMID : 11577112






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we trace the hypocholesterolemic activity of LY295427 to an ability to reverse oxysterol-mediated suppression of sterol regulatory element-binding protein (SREBP) processing. Oxysterols CCHC-type zinc finger nucleic acid binding protein Homo sapiens
2 Here we trace the hypocholesterolemic activity of LY295427 to an ability to reverse oxysterol-mediated suppression of sterol regulatory element-binding protein (SREBP) processing. Oxysterols CCHC-type zinc finger nucleic acid binding protein Homo sapiens
3 LY295427 overcame the suppression of SREBP processing mediated by several oxysterols but not by LDL-derived cholesterol. Oxysterols CCHC-type zinc finger nucleic acid binding protein Homo sapiens