Title : Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.

Pub. Date : 2001 Oct

PMID : 11574405






1 Functional Relationships(s)
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1 Glucose- and insulin-stimulated translocation of PDX-1 to the nucleoplasm was inhibited by wortmannin and SB 203580, indicating that a pathway involving PI 3-kinase and SAPK2/p38 was involved; translocation was unaffected by PD 098959 and rapamycin, suggesting that neither mitogen-activated protein kinase nor p70(s6k) were involved. SB 203580 ubiquitin associated and SH3 domain containing B Homo sapiens