Title : Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides.

Pub. Date : 2001 Dec 21

PMID : 11560922






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclic AMP, which completely blocks platelet function, inhibited the -induced activation of G(q) and G(12)/G(13) as well as of Rac and Rho. Cyclic AMP AKT serine/threonine kinase 1 Homo sapiens
2 Cyclic AMP and cGMP differentially interfere with -induced Rho and Rac activation at least in part by selective effects on the regulation of individual G-proteins through the TXA(2) receptor. Cyclic AMP AKT serine/threonine kinase 1 Homo sapiens