Title : Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate.

Pub. Date : 2001 Oct

PMID : 11557524






1 Functional Relationships(s)
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1 Substitution of Leu at position 1084 of rat MRP3 (which corresponds to Arg-1096 in rat MRP2) with Lys, but not with Val or Met, resulted in the loss of transport activity for TC and glucuronide conjugates. Glucuronides ATP binding cassette subfamily C member 3 Rattus norvegicus